Deep reflection-mode photoacoustic imaging of biological tissue
نویسندگان
چکیده
منابع مشابه
Deep reflection-mode photoacoustic imaging of biological tissue.
A reflection-mode photoacoustic (PA) imaging system was designed and built to image deep structures in biological tissues. We chose near-infrared laser pulses of 804-nm wavelength for PA excitation to achieve deep penetration. To minimize unwanted surface signals, we adopted dark-field ring-shaped illumination. This imaging system employing a 5-MHz spherically focused ultrasonic transducer prov...
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Compared with single-focus optical-resolution photoacoustic microscopy (OR-PAM), multifocal OR-PAM utilizes both multifocal optical illumination and an ultrasonic array transducer, significantly increasing the imaging speed. A reflection-mode multifocal OR-PAM system based on a microlens array that provides multiple foci as well as an ultrasonic array transducer that receives the excited photoa...
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Photoacoustic imaging (PAI), a novel imaging modality based on photoacoustic effect, shows great promise in biomedical applications. By converting pulsed laser excitation into ultrasonic emission, PAI combines the advantages of optical imaging and ultrasound imaging, which benefits rich contrast, high resolution and deep tissue penetration. In this paper, we introduced recent advances of contra...
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For deep tissue photoacoustic imaging, piezoelectric ultrasound detectors with large element sizes (>1mm) and relatively low centre frequencies (<5MHz) are generally used, as they can provide the required high sensitivity to achieve imaging depths of several centimetres. However, these detectors are generally not optimised in terms of element size and bandwidth. To identify these parameters in ...
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2007
ISSN: 1083-3668
DOI: 10.1117/1.2818045